Enzymes of carbohydrate metabolism in naevoid basal-cell epithelioma

The activities of 27 enzymes of carbohydrate metabolism and the proportions of lactate dehydrogenase isoenzymes were determined in epidermis, in superficial epitheliomas and in several solid tumours biopsied from a patient with basal-cell naevus syndrome. The activity patterns varied from that of normal epidermis to that found in basal-cell epitheliomas. Thickened epidermis, superficial epitheliomas and some of the solid tumours presented an intermediate pattern. Histologically similar lesions sometimes differed markedly in their enzyme activities.