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Depression and short REM latency in subjects with chronic fatigue syndrome
R L Morehouse1, M Flanigan, D D MacDonald
1Department of Psychiatry, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia.
Objective:
The hypothesized polysomnographic marker for depression, Rapid Eye Movement Latency (REML), was used to investigate two groups of subjects; Chronic Fatigue Syndrome (CFS)-not depressed and CFS-depressed.
Method:
CFS subjects were classified into depressed and not depressed groups, using the Diagnostic Interview Schedule (DIS), and subsequently were studied in a sleep laboratory to ascertain REML.
Results:
Short REML showed a statistically significant correlation with the depressed state in CFS subjects.
Conclusion:
Short REM latency is associated with depression in the CFS population.
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