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Quantification of mitral regurgitation with MR phase-velocity mapping using a control volume method
G P Chatzimavroudis1, J N Oshinski, R I Pettigrew
1Cardiovascular Fluid Mechanics Laboratory, School of Chemical Engineering, Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta 30332-0100, USA.
Journal of Magnetic Resonance Imaging : JMRI
|June 17, 1998
Summary
This study shows a new control volume (CV) method accurately quantifies mitral regurgitation volume (MRV). The CV method offers a promising approach for reliable mitral regurgitation diagnosis and surgical timing.
Area of Science:
- Cardiovascular imaging
- Medical physics
- Fluid dynamics
Background:
- Accurate quantification of mitral regurgitation (MR) is crucial for patient management and surgical decision-making.
- Existing methods for MR quantification often yield suboptimal results, necessitating improved techniques.
Purpose of the Study:
- To evaluate the efficacy of MR phase-velocity mapping using a control volume (CV) method for quantifying mitral regurgitant volume (MRV).
Main Methods:
- Acquisition of contiguous slices with three-component velocity measurements.
- Selection of a control volume (CV) encompassing the regurgitant orifice.
- Application of mass conservation principles to calculate regurgitant flow based on net inflow into the CV.
Main Results:
- Accurate MRV measurements were achieved when the CV boundary excluded regions of flow acceleration and aliasing at the orifice.
- Smaller CVs resulted in erroneous measurements due to flow acceleration and aliasing.
- Larger CVs led to inaccurate results due to decreased velocity sensitivity.
- Aortic outflow, orifice shape, and valve geometry did not impact the accuracy of CV measurements.
Conclusions:
- The control volume (CV) method, when appropriately defined, provides accurate quantification of mitral regurgitant volume (MRV).
- This technique shows promise as a reliable tool for assessing mitral regurgitation severity.