[Asymmetrical behavior of small intestine epithelium under osmotic pressure]

The influence of wide interval of osmotic gradients on transepithelial potential differences through small intestine were investigated. It was found, that ion permeability begins to rise at osmotic pressures equal to 0.200-0.250 osmomol on serosal side and 0.350-0.400 osomomol on mucosal side. The variatin in behaviour of osmotic potential differences caused by flows directed from mucosal solution to serosal one and in the reverse direction at smaller osmotic pressure is shown. An assumption was made that observed features of behaviour of osmotic potential differences were due to structural reorganization in intracellular junction.