Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Encapsulated cell technology

R P Lanza1, J L Hayes, W L Chick

  • 1BioHybrid Technologies Inc., Shrewsbury, MA 01545-3303, USA. rtla@aol.com

Nature Biotechnology
|September 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Profiling cytotoxic microRNAs in pediatric and adult glioblastoma cells by high-content screening, identification, and validation of miR-1300.

Oncogene·2020
Same author

Repellent properties of the host compound 4-allylanisole to the southern pine beetle.

Journal of chemical ecology·2013
Same author

Diagnosis of copy number variation by Illumina next generation sequencing is comparable in performance to oligonucleotide array comparative genomic hybridisation.

Genomics·2013
Same author

The use of local anaesthesia in haemorrhoidal banding: a randomized controlled trial.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2013
Same author

Encapsulation technologies.

Tissue engineering·2009
Same author

Surgical versus medical methods for second trimester induced abortion.

The Cochrane database of systematic reviews·2008
Same journal

Prime editing for precise genome engineering and modulation of fungal metabolism.

Nature biotechnology·2026
Same journal

Retargeted serine integrases for one-step, precise integration of large DNA sequences in human cells.

Nature biotechnology·2026
Same journal

A retargeted recombinase for precise insertion of large DNA.

Nature biotechnology·2026
Same journal

Experiment-guided AlphaFold3 resolves measurement-consistent protein ensembles.

Nature biotechnology·2026
Same journal

Spatially resolved profiling of extracellular vesicles in tissues with Spatial-EV-seq.

Nature biotechnology·2026
Same journal

Mapping the spatial landscape of extracellular vesicles in tissues with Spatial-EV-seq.

Nature biotechnology·2026
See all related articles

Encapsulated cell therapy holds vast potential for treating numerous diseases, including neurodegenerative disorders and diabetes. Clinical trials are anticipated soon, pending the resolution of manufacturing and quality control challenges.

Area of Science:

  • Biotechnology
  • Regenerative Medicine
  • Cell Therapy

Background:

  • Significant healthcare costs are associated with tissue loss and dysfunction, impacting millions with conditions like Alzheimer's, Parkinson's, and diabetes.
  • Cellular dysfunction underlies a wide range of serious diseases, highlighting the need for novel therapeutic strategies.
  • Encapsulated cell technology offers a promising approach to restore vital cellular functions.

Purpose of the Study:

  • To highlight the immense therapeutic potential of encapsulated cells.
  • To underscore the urgent need for cell-based therapies in treating prevalent chronic diseases.
  • To outline the anticipated timeline for clinical applications and regulatory approval.

Main Methods:

  • Review of current therapeutic strategies for tissue loss and cellular dysfunction.

Related Experiment Videos

  • Analysis of the market and patient impact of diseases like Alzheimer's, Parkinson's, and diabetes.
  • Examination of the regulatory landscape and requirements for novel cell therapies.
  • Main Results:

    • Encapsulated cell therapy is poised for significant clinical development within the decade.
    • The Food and Drug Administration (FDA) has initiated studies to assess the safety and efficacy of encapsulated cell systems.
    • Substantial investment and research are driving the advancement of this technology.

    Conclusions:

    • Encapsulated cell therapy represents a transformative approach to treating a broad spectrum of diseases.
    • Addressing manufacturing, scale-up, and quality control are critical next steps for clinical translation.
    • The convergence of scientific advancement and regulatory support suggests a promising future for encapsulated cell therapeutics.