Related Experiment Videos
Long-term thrombosis after transvenous permanent pacemaker implantation
1Department of Cardiovascular Surgery, Akita University, Akita Medical Center, Japan.
Pacing and Clinical Electrophysiology : PACE
|June 20, 1998
Summary
Venous thrombosis occurs in 23% of patients after long-term transvenous pacemaker implantation. This study could not determine if anticoagulant drugs prevent this complication, necessitating further research.
Area of Science:
- Cardiology
- Vascular Surgery
Background:
- Long-term transvenous permanent pacemaker implantation can lead to venous thrombosis.
- The efficacy of prophylactic anticoagulant and antiaggregant drugs in preventing this complication is not well-established.
Purpose of the Study:
- To assess the incidence of venous thrombosis after long-term transvenous permanent pacemaker implantation.
- To evaluate the potential efficacy of prophylactic anticoagulant and antiaggregant drugs in preventing venous thrombosis.
Main Methods:
- Venograms were performed in 100 patients undergoing elective pacemaker replacement after a mean follow-up of 6.0 years.
- Patient data regarding lead characteristics and medication use were analyzed retrospectively.
Main Results:
- Venous abnormalities, including stenosis and total obstruction, were found in 23% of patients.
- No significant difference in venous abnormalities was observed based on the route of entry, lead insulation, number of leads, or use of anticoagulant/antiaggregant drugs.
- All patients with venous abnormalities remained asymptomatic, with 21 exhibiting collateral circulation.
Conclusions:
- The incidence of venous thrombosis after long-term transvenous pacing is 23%, potentially caused by endothelial trauma and venous stenosis.
- This retrospective study could not establish the efficacy of prophylactic anticoagulant and antiaggregant drugs.
- Further prospective studies are required to determine the effectiveness of these prophylactic measures.