Images of psychopathology

Brain imaging continues to provide important data about brain structure, neurotransmitter function and the physiological basis of cognitive processes, as these relate to schizophrenia and mood disorders. A unifying theoretical perspective, however, that can clarify the precise nature of the biological basis of these diverse psychiatric conditions is lacking. It is becoming increasingly evident that a lesion model is inappropriate and that a more relevant characterisation will be found in terms of disorders of functional interconnections between brain regions.