Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radionuclide cancer therapy

C A Hoefnagel1

  • 1Department of Nuclear Medicine, The Netherlands Cancer Center Institute, Amsterdam.

Annals of Nuclear Medicine
|June 24, 1998
PubMed
Summary
This summary is machine-generated.

Therapeutic nuclear medicine offers a selective, non-invasive oncology treatment. This approach uses radiopharmaceuticals for targeted radiation delivery, with pre-assessable tumor uptake, minimizing side effects.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparison of targetting of neuroblastoma with mIBG and anti L1-CAM antibody mAb chCE7: therapeutic efficacy in a neuroblastoma xenograft model and imaging of neuroblastoma patients.

European journal of nuclear medicine·2014
Same author

Radionuclide Imaging of Apoptosis in Malignancies: Promise and Pitfalls of Tc-Hynic-rh-Annexin V Imaging.

Clinical medicine. Oncology·2011
Same author

The pharmacokinetics of ¹³¹I-rituximab in a patient with CD20 positive non-Hodgkin Lymphoma: evaluation of the effect of radioiodination on the biological properties of rituximab.

Human antibodies·2011
Same author

[Added value of prone position technique for PET-TAC in breast cancer patients].

Revista espanola de medicina nuclear·2010
Same author

Intraoperative radioguidance with a portable gamma camera: a novel technique for laparoscopic sentinel node localisation in urological malignancies.

European journal of nuclear medicine and molecular imaging·2009
Same author

[Regional lymph nodes at a distance].

Nederlands tijdschrift voor geneeskunde·2008
Same journal

The Prognostic Value of <sup>68</sup>Ga-PSMA and <sup>18</sup>F-FDG PET/CT in Metastatic Castration-Resistant Prostate Cancer Treated with <sup>177</sup>Lu-EB-PSMA.

Annals of nuclear medicine·2026
Same journal

Atomic degradation: chemical design strategies and immunotherapeutic mechanisms of radio-PROTACs.

Annals of nuclear medicine·2026
Same journal

Impact of biguanide therapy on hepatic <sup>18</sup>F-fluorodeoxyglucose-positron emission tomography quantitative parameters in patients with diabetes: a dynamic positron emission tomography study.

Annals of nuclear medicine·2026
Same journal

Dual-time-point 68Ga-FAPI PET/CT in gastrointestinal malignancies: head-to-head comparison with 18 F-FDG for lesion detection and patient-level assessment.

Annals of nuclear medicine·2026
Same journal

Bloodpool SPECT/CT offers enhanced sensitivity for the diagnosis of frozen shoulder.

Annals of nuclear medicine·2026
Same journal

Adsorption treatment of <sup>177</sup>Lu radioactive wastewater with <sup>177m</sup>Lu impurity: batch versus column methods.

Annals of nuclear medicine·2026
See all related articles

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiopharmaceutical Therapy

Background:

  • Therapeutic nuclear medicine is an emerging oncology treatment modality.
  • It offers systemic yet selective radiation delivery to target tissues.
  • Advantages include non-invasiveness, fewer side effects, and pre-assessable tumor uptake.

Purpose of the Study:

  • To review the current clinical role of radionuclide therapy in oncology.
  • To discuss general aspects and considerations for radiopharmaceutical therapy.
  • To highlight mechanisms for tumor targeting and radiopharmaceutical selection.

Main Methods:

  • Review of current clinical applications of therapeutic nuclear medicine.
  • Discussion of tumor targeting mechanisms.

Related Experiment Videos

  • Consideration of radionuclide selection, radiopharmacy, drug delivery, and dosimetry.

    • Main Results:

    • Radiopharmaceutical therapy provides targeted radiation with pre-assessable tumor uptake.
    • Various radiopharmaceuticals and targeting mechanisms are employed.
    • The review covers essential aspects from radiopharmacy to toxicity.

    Conclusions:

    • Therapeutic nuclear medicine is a valuable and developing treatment option in oncology.
    • Effective implementation requires careful consideration of targeting, radionuclide choice, and delivery.
    • Further advancements promise improved patient outcomes with minimized toxicity.