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Body composition in patients treated with peritoneal dialysis
A C Johansson1, O Samuelsson, B Haraldsson
1Department of Nephrology, Sahlgrenska University Hospital, Göteborg, Sweden.
Summary
Long-term peritoneal dialysis may reduce body cell mass while maintaining or increasing body fat. This study analyzed nutritional status in patients undergoing peritoneal dialysis, revealing potential risks to body cell mass over time.
Area of Science:
- Nephrology
- Nutritional Science
- Biomedical Engineering
Background:
- Malnutrition is a frequent complication in patients with uremia and undergoing maintenance dialysis.
- Several contributing factors influence the development of malnutrition.
- Different dialysis modalities may impact patient nutritional status differently.
Purpose of the Study:
- To analyze the nutritional consequences of peritoneal dialysis (PD).
- To assess changes in body composition during PD treatment.
Main Methods:
- Body composition analyses were performed in PD patients.
- Body cell mass (BCM) estimated from total body potassium (TBK).
- Total body water (TBW) and body fat (BF) were determined and calculated.
Main Results:
- No overall change in body composition in the first year of PD.
- Significant decline in TBK and increase in BF observed in the second and third years of PD.
- Individual changes in body weight correlated with changes in body fat.
Conclusions:
- Long-term PD treatment may pose a risk of reduced body cell mass.
- Body energy stores (body fat) may be maintained or increased during long-term PD.
- Further research is needed to mitigate risks to body cell mass in PD patients.