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Electrical properties of glucose-sensitive hydrogels: swelling and conductivity relationships
M Schwartz1, H Guterman, J Kost
1Program for Biotechnology, Ben Gurion University of the Negev, Beer-Sheva, Israel.
Journal of Biomedical Materials Research
|June 26, 1998
Abstract:
The electrical characteristics of a glucose-sensitive polymeric hydrogel have been studied. The hydrogel matrices were prepared by radical polymerization of solutions containing 2-hydroxyethyl methacrylate, N,N-dimethyl aminoethyl methacrylate, tetraethylene glycol dimethacrylate, ethylene glycol, water, and glucose oxidase. The hydrogels displayed faster and higher swelling rates for lower levels of a crosslinking agent. Electrical conductivity was found to be a sensitive measurement of the state of the swelling. A simple model that relates hydrogel swelling and conductivity has been proposed.