Related Experiment Video
Updated: May 21, 2026
10:25
Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
Candida esophagitis: a prospective study of 27 cases
Gastroenterology
|November 1, 1976
Summary
Candida esophagitis was diagnosed in 27 patients via endoscopy and microscopy. Treatment with nystatin or flucytosine effectively cleared symptoms and lesions in most cases.
Area of Science:
- Gastroenterology
- Mycology
- Infectious Diseases
Background:
- Candida esophagitis is an opportunistic infection.
- Diagnosis and treatment spectrum in a general hospital setting were investigated.
Purpose of the Study:
- To determine the spectrum of Candida esophagitis in a general hospital.
- To evaluate diagnostic criteria and treatment efficacy.
Main Methods:
- Prospective study involving 370 endoscopies over 1 year.
- Diagnosis based on endoscopic plaques, microscopy, and serum agglutinin titers (≥1:160).
- Treatment with nystatin or nystatin and flucytosine, followed by re-endoscopy.
Main Results:
- 27 cases of Candida esophagitis detected; 14 presented with esophageal symptoms.
- Nine out of twelve treated patients showed symptom resolution and lesion clearance.
- Control groups had low rates of positive titers (4-17%), with absence of titer precluding diagnosis.
Conclusions:
- Candida esophagitis can be diagnosed using a combination of clinical, endoscopic, microscopic, and serological findings.
- Antifungal therapy, including nystatin and flucytosine, is effective in treating Candida esophagitis.
- Serum agglutinin titers are valuable in diagnosing Candida esophagitis.
