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Rifabutin-associated uveitis in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome
D A Jewelewicz1, W M Schiff, S Brown
1Edward S. Harkness Eye Institute, Columbia Presbyterian Medical Center, New York, NY 10032, USA. daj17@columbia.edu
Purpose:
To describe a case of bilateral, symptomatic rifabutin-associated uveitis with hypopyon and vitreal opacities in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome (AIDS).
Method:
Case report. An 8-year-old boy presented with bilateral uveitis 24 months after a bilateral lung transplant.
Results:
Our patient, whose medications included rifabutin, clarithromycin, and immunosuppressive agents, responded to discontinuation of the rifabutin and initiation of intensive topical corticosteroid therapy with complete resolution of the uveitis.
Conclusion:
Rifabutin-associated uveitis may occur in a non-AIDS pediatric patient.
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