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Repeated hepatectomy for colorectal metastasis
V Di Carlo1, P De Nardi, G Ferrari
1Department of General Surgery, S. Raffaele Hospital, University of Milan, Italy.
Annali Italiani Di Chirurgia
|July 1, 1998
Summary
Second liver resection for recurrent colorectal metastases offers a chance for long-term survival. Careful patient selection and surgical technique are crucial for successful outcomes in repeat hepatic resections.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Gastrointestinal Oncology
Background:
- Colorectal cancer frequently metastasizes to the liver.
- Repeat liver resection is considered for isolated liver recurrence after initial surgery.
- Limited data exists on outcomes of second liver resections for colorectal metastases.
Purpose of the Study:
- To evaluate the outcomes of second liver resection in patients with isolated liver recurrence from colorectal metastases.
- To identify factors associated with survival after repeat hepatic resection.
Main Methods:
- Retrospective analysis of 12 patients undergoing second liver resection for isolated colorectal liver metastases between 1981 and 1995.
- Data collected on patient characteristics, tumor burden, surgical procedures, and follow-up outcomes.
- Actuarial survival and disease-free survival rates were calculated.
Main Results:
- No perioperative mortality was observed in 12 patients.
- Morbidity rate was 33%, with no significant association between patient/tumor characteristics and survival.
- Three-year and 5-year actuarial survival rates were 71% and 42%, respectively; 3-year disease-free survival was 30%.
Conclusions:
- Second liver resection for recurrent colorectal metastases can achieve long-term survival and potential cure in selected patients.
- Careful patient selection and meticulous surgical technique are paramount to minimize postoperative complications.
- Surgical resection remains the only curative option for isolated liver recurrence of colorectal cancer.