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Updated: Jul 31, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
The newborn at risk for serious infections
1Department of Pediatrics, Lovelace Health System, Albuquerque, New Mexico, USA.
Insights
Early newborn discharge is safe if hospitals follow national guidelines. This practice does not increase the risk of serious infections like neonatal sepsis or herpes, provided risk factors are monitored.
Area of Science:
- Neonatal care
- Infectious disease epidemiology
Background:
- Early newborn discharge is a growing hospital trend.
- Concerns exist regarding the potential for missed early signs of serious neonatal infections.
Purpose of the Study:
- To analyze the risk of treatable neonatal infections with early discharge.
- To determine if current early discharge practices endanger newborns.
Main Methods:
- Review of existing data on early-onset neonatal bacterial sepsis.
- Analysis of data concerning neonatal herpes virus infection.
Main Results:
- Early discharge does not appear to significantly increase the risk of serious treatable infections.
- Adherence to conventional risk factors and national discharge criteria is crucial.
Conclusions:
- Early newborn discharge can be a safe standard practice.
- Vigilance for risk factors and adherence to discharge guidelines mitigate infection risks.
Abstract:
Early discharge of suitable newborns is rapidly becoming a hospital standard. One concern is that truncated hospital observation of the infant during the first days of life, even with home visits or early clinical appointments, would allow early signs of a serious infection to go unnoticed, which could lead to a missed chance for early therapy and could imperil the child's favorable recovery. An analysis of available data for early onset neonatal bacterial sepsis and neonatal herpes virus infection shows that this new practice should not unduly place newborns at risk of treatable infections, however, so long as conventional risk factors are appreciated and reasonable, nationally sanctioned discharge criteria are followed.
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