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Summary
Acromegalic dysphonia affects most patients, but objective voice changes occur in only half. Objective dysphonia is linked to specific acromegaly characteristics like facial changes and longer disease duration.
Area of Science:
- Endocrinology
- Otolaryngology
- Speech and Voice Science
Context:
- Acromegaly, a condition caused by excess growth hormone, can affect various bodily systems.
- Voice changes (dysphonia) are a potential but not fully understood symptom in acromegaly patients.
Purpose:
- To investigate the prevalence and characteristics of dysphonia in a cohort of 80 acromegalic patients.
- To identify factors associated with the development of objective dysphonia in acromegaly.
Summary:
- Subjective dysphonia was reported by a majority of the 80 acromegalic patients.
- Objective dysphonia was present in 50% of patients, often associated with facial changes (progenia), significant acromegalic activity, and disease duration exceeding five years.
Impact:
- Highlights the prevalence of voice disturbances in acromegaly.
- Identifies key clinical factors (progenia, disease activity, duration) predictive of objective dysphonia, aiding in patient assessment and management.