Related Experiment Videos
Amantadine: a potential treatment for the minimally conscious state
R D Zafonte1, T Watanabe, N R Mann
1Rehabilitation Institute of Michigan, Wayne State University, Detroit, USA.
Brain Injury
|July 8, 1998
Abstract:
Pharmacologic strategies have been advocated to enhance the neurorehabilitation of persons with severe traumatic brain injury. Dopaminergic pathways have been felt to play a significant role in arousal. Employing single case design methodology we present the case of a survivor of severe traumatic brain injury who appeared to have a dose dependent response to the pro-dopaminergic medication amantadine. Further research is necessary to clarify the role of pharmacotherapy in the improvement of functional outcome.