Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Unilateral parathyroid exploration

L M Vogel1, R Lucas, P Czako

  • 1William Beaumont Hospital, Royal Oak, Michigan, USA.

The American Surgeon
|July 9, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rates of Sexual Harassment Among Emergency Medicine Faculty and the Impact on Faculty Engagement.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2026
Same author

Endothelial ENaC as a repressor of oxidative stress and a guardian of lung capillary barrier function in bacterial and viral pneumonia.

Frontiers in physiology·2025
Same author

Insomnia and nightmare profiles during the COVID-19 pandemic in Portugal: characterization and associated factors.

Sleep medicine·2022
Same author

Needs Assessment to Inform and Improve Educational Practices Surrounding Omega-3 Consumption during Pregnancy.

Maternal and child health journal·2021
Same author

Standardizing Ecosystem Morphological Traits from 3D Information Sources.

Trends in ecology & evolution·2020
Same author

Measurements of the associated production of a Z boson and b jets in pp collisions at <math> </math>.

The European physical journal. C, Particles and fields·2020
Same journal

What the Salary Rankings Miss About Pediatric Surgery: Readiness, Not Compensation.

The American surgeon·2026
Same journal

Contrast Without Clarity: The Questionable Role of Oral Contrast in Detecting Missed Hollow Viscus Injury.

The American surgeon·2026
Same journal

Learning Surgery's Moral Questions: Mentorship, Reflection, and Professional Formation.

The American surgeon·2026
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
See all related articles

Unilateral neck exploration (UNE) for primary hyperparathyroidism offers excellent results comparable to bilateral neck exploration (BNE). This approach reduces operative time and complications when guided by accurate preoperative ultrasound localization.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Radiology

Background:

  • Primary hyperparathyroidism is often caused by a single parathyroid adenoma.
  • Surgical management aims for curative resection with minimal morbidity.
  • Traditional bilateral neck exploration (BNE) is effective but can lead to longer operative times and increased complications.

Purpose of the Study:

  • To evaluate the efficacy and safety of unilateral neck exploration (UNE) for primary hyperparathyroidism.
  • To determine the accuracy of preoperative ultrasound (US) in guiding UNE.
  • To compare operative outcomes between UNE and BNE.

Main Methods:

  • Retrospective review of 106 patients with primary hyperparathyroidism operated on between May 1989 and October 1996.
  • Preoperative ultrasound (US) was performed in 77 patients by a specialized radiologist.

Related Experiment Videos

  • UNE was performed when US findings localized the pathology to one side and operative findings were consistent.

    • Main Results:

    • Ultrasound accuracy for parathyroid localization was 90% when performed by an interested radiologist.
    • Patients undergoing UNE had significantly shorter operative times (P = 0.001) compared to BNE.
    • UNE demonstrated a significantly lower complication rate (22%) compared to BNE (45%, P = 0.04), primarily due to fewer cases of hypocalcemia.

    Conclusions:

    • Unilateral neck exploration (UNE) is a safe and effective surgical approach for primary hyperparathyroidism when guided by accurate preoperative ultrasound localization.
    • UNE offers significant advantages over BNE, including reduced operative time, decreased morbidity, and avoidance of contralateral neck scarring.
    • Accurate, noninvasive, and cost-effective preoperative localization studies, such as parathyroid US, are crucial for successful implementation of UNE.