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Peripheral polyneuropathy due to chronic use of topical ammoniated mercury
D Deleu1, Y Hanssens, H S al-Salmy
1College of Medicine, Sultan Qaboos University, Al-Khod, Muscat, Sultanate of Oman. deleu@gto.net.om
Background:
Despite their potentially disastrous side effects, topical mercury salts can still be found as ingredients in some over-the-counter preparations or local remedies.
Case Report:
Peripheral polyneuropathy as a result of chronic ammoniated mercury poisoning was studied and followed over 2 years. A 36-year-old man developed peripheral polyneuropathy following chronic perianal use of an ammoniated mercury ointment. Highly elevated blood and urine mercury levels were found. Sural nerve biopsy showed mixed axonal degeneration-demyelination. There was progressive improvement of his symptoms over 2 years but neurophysiological examination revealed incomplete recovery.
Conclusion:
The availability of safer drugs should result in a complete ban of these dangerous compounds.
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