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[Otoneurologic abnormalities in insulin-dependent diabetes]
K Jáuregui-Renaud1, B Domínguez-Rubio, A Ibarra-Olmos
1Departamento de Audiología y Otoneurologia, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, México DF. kjauren@data.net.mx
Objective:
To assess the auditory and vestibular function in patients with diabetes.
Material And Methods:
We studied and followed for three years, 10 patients (6 females) of 20.6 years of age (SD 5.5 years), with insulindependent diabetes mellitus of 9.5 years (SD 3.7 years). The patients were selected for having peripheral neuropathy without prolipherative retinopathy and otologic disease or individual factors which could cause neurootologic symptoms. Their glomerular filtration rate and renal plasma flow were 150 mL/min (SD 50) and 543 mL/min (SD 113).
Results:
Initially all patients had normal audiologic responses, including auditory brainstem responses, but had abnormally and simetrically diminished horizontal vestibulo-ocular responses. A year later one patient had vertigo and asymmetric vestibulo-ocular responses. In the third year, another patient showed similar abnormalities and a third one showed sensorineural hearing loss.
Conclusion:
Our results suggest that patients with insulindependent diabetes mellitus may suffer neuro-otological deterioration.