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Pathophysiological chemistry of nitric oxide and its oxygenation by-products
1Department of Chemistry, University of Wyoming, Laramie, WY 82071-3838, USA. bohle@uwyo.edu
Current Opinion in Chemical Biology
|July 17, 1998
Abstract:
Nitric oxide is not only an important intracellular regulator and cytostatic effector but it is also the starting point for a cascade of physiologically important oxygenation reactions, whose by-products and intermediates have a largely unexplored biochemistry. These new biological discoveries are reshaping our appreciation of the remarkably complex chemistry that underlies it.