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An in vitro model of human erythropoiesis for the study of hemoglobinopathies

P Malik1, L L Barsky, L Zeng

  • 1Division of Hematology-Oncology, Children's Hospital Los Angeles. CA 90027, USA. malik@hsc.usc.edu

Annals of the New York Academy of Sciences
|July 21, 1998
PubMed
Abstract

No abstract available in PubMed .

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Erythropoiesis01:14

Erythropoiesis

Red blood cells  (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia, and...