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[The characteristics of poliovirus strains circulating in Ukraine in 1982-1994]

V I Zadorozhnaia1, V I Bondarenko, L I Siniak

  • 1Scientific Research Institute of Epidemiology and Infectious Diseases, Kyiv, Ukraine.

Mikrobiolohichnyi Zhurnal (Kiev, Ukraine : 1993)
|July 22, 1998
PubMed

Insights

Even after years of live polio vaccination, virulent polioviruses persist. This study found over 38% of poliovirus strains from people and 15% from the environment in Ukraine were virulent.

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Context:

  • Poliovirus circulation in Ukraine between 1982-1994.
  • Analysis of poliovirus strains from human and environmental sources.

Purpose:

  • To characterize intratype polioviruses isolated in Ukraine.
  • To assess the impact of long-term live polio vaccine use on poliovirus virulence.

Summary:

  • 219 poliovirus strains were analyzed from patients, healthy individuals, and environmental samples.
  • 38.35% of human-isolated strains and 15.12% of environmental strains exhibited virulent properties.

Impact:

  • Demonstrates the continued circulation of virulent polioviruses despite extensive vaccination efforts.
  • Highlights potential risks to public health from vaccine-resistant poliovirus strains.

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