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Related Experiment Videos

Microarrays: biotechnology's discovery platform for functional genomics

M Schena1, R A Heller, T P Theriault

  • 1Department of Biochemistry, Beckman Center, Stanford University Medical Center, CA 94305, USA.

Trends in Biotechnology
|July 24, 1998
PubMed
Summary

Microarray technology allows large-scale biological data analysis. These

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Area of Science:

  • Genomics and molecular biology
  • Biotechnology and bioinformatics

Background:

  • Microarray technology facilitates high-throughput biological data analysis.
  • Hybridization-based methods on biological chips enable expression monitoring, polymorphism detection, and genotyping.

Purpose of the Study:

  • To highlight the potential of advanced microarray technology for comprehensive genomic analysis.
  • To underscore the impact of 'genome chips' on human health research.

Main Methods:

  • Utilizing microarray technology for massive parallel data mining.
  • Employing hybridization-based expression monitoring, polymorphism detection, and genotyping.

Main Results:

  • Microarrays offer genomic-scale analysis capabilities.

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  • Future 'genome chips' promise whole-genome expression analysis in a single reaction.

    • Conclusions:

    • Microarray technology is a pivotal tool in functional genomics.
    • This technology offers significant advancements in understanding human health, disease, and drug discovery.