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[Bilateral 3rd cranial nerve palsy disclosing oligodendroglioma]
X Douay1, C Daems-Monpeurt, P Labalette
1Clinique Neurologique, Hôpital Roger Salengro, Lille.
Revue Neurologique
|July 1, 1997
Summary
A rare case of high-grade oligodendroglioma presented as bilateral third cranial nerve palsy. Early neuroradiological imaging is crucial for diagnosing cranial nerve palsies with suspected tumors.
Area of Science:
- Neuro-oncology
- Neurology
- Ophthalmology
Background:
- Oligodendrogliomas are rare primary brain tumors.
- Third cranial nerve palsy typically presents with specific ocular motor deficits.
Observation:
- A 30-year-old male presented with several months of horizontal diplopia.
- Clinical examination revealed bilateral third cranial nerve palsy with intact pupillary function.
- Initial investigations for myasthenia gravis were negative.
Findings:
- CT and MRI identified an atypical left temporo-insular lesion.
- Cerebral biopsy confirmed a high-grade oligodendroglioma.
- The tumor's location suggested infiltration of the cerebral peduncles as the cause of palsy.
Implications:
- This case highlights an unusual presentation of oligodendroglioma.
- Highlights the importance of early and thorough neuroradiological evaluation in cranial nerve palsies.
- Suggests considering brain tumors in the differential diagnosis of unexplained cranial nerve palsies.