Endothelial cells lining polyester fabric express pro-coagulant phenotype in vitro
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Updated: Oct 29, 2026
In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time
Published on: May 24, 2020
M Rémy1, R Bareille, F Villars
1INSERM U 443, Université Victor Segalen Boreaux, France. U443@bordeaux.inserm.fr
Abstract:
The paper deals with the in vitro assessment of endothelial cell (EC) phenotype covering an albumin- and chitosan-coated polyester fabric and shows that resting ECs express a pro-coagulant phenotype by releasing a high von Willebrand factor level and expressing low thrombomodulin surface activity, despite maintaining an adequate response to stimulating agents.
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