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Updated: Aug 6, 2026

Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
Published on: March 17, 2012
[Association of amyotrophic lateral sclerosis with scleroderma. Study of 2 cases]
H Ouhabi1, A Bourazza, A Rouimi
1Service de Neurologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Abstract:
We report a clinical association of diffuse scleroderma and amyotrophic lateral sclerosis (ALS) in two patients. Scleroderma was diagnosed on skin, digestive, osteoarticular, pulmonary lesions and inflammatory syndrome. ALS was suspected on the association of diffuse amyotrophy, fasciculations, pyramidal tract involvement and electrophysiological data. Chronic medulla ischemia and or immune abnormalities are proposed as potential pathological mechanisms for ALS but fortuitous association can not be excluded.
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