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Normal and lethal mercury levels in human beings

M I Hilmy, S A Rahim, A H Abbas

    Toxicology
    |August 1, 1976
    PubMed
    Summary
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    Ingesting mercury-treated grain bread caused mercury poisoning in Iraqi villagers. Tissue analysis revealed high ethyl mercury levels in kidneys, liver, cerebellum, and blood.

    Area of Science:

    • Environmental Toxicology
    • Analytical Chemistry
    • Public Health

    Background:

    • Ethyl mercury fungicide (Granosan M) was used on grains in Iraq.
    • Villagers consumed treated grain for bread, ignoring safety warnings.

    Purpose of the Study:

    • To analyze total mercury content in tissues of individuals with suspected mercury poisoning.
    • To quantify mercury levels in various organs and blood.

    Main Methods:

    • Flameless atomic absorption spectroscopy (AAS) was employed for mercury analysis.
    • The highly sensitive method achieved 1 ppb sensitivity and 1.5% relative standard deviation (RSD).

    Main Results:

    • Elevated mercury levels were detected in multiple tissues.

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  • Specific ranges found: kidneys (8-9 ppm), livers (6-7 ppm), cerebellum (3-5 ppm), and blood (approx. 15 ppm).
  • Control tissue samples from non-poisoned individuals were analyzed for comparison.

    • Conclusions:

    • Consumption of mercury-treated grain led to significant mercury accumulation in human tissues.
    • The study highlights the severe health risks associated with improper use of ethyl mercury fungicides.