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Published on: May 7, 2019
End-stage renal disease (ESRD)after bone marrow transplantation: poor survival compar ed to other causes of ESRD
E P Cohen1, W F Piering, C Kabler-Babbitt
1Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisc., USA. ecohen@mcw.edu
Abstract:
Chronic renal failure after successful bone marrow transplantation (BMT) may diminish the quality of life and may also evolve to end-stage renal disease (ESRD) requiring chronic dialysis. Individual reports suggest poor survival of such patients. We evaluated the survival with ESRD after BMT by the case-control method. We found that patients who develop ESRD after BMT have a significantly decreased survival as compared with non-BMT patients. This was true for both diabetic and nondiabetic ESRD (both p < 0.03). These data demonstrate the poor outcome of ESRD after BMT which emphasizes the need for a better understanding of chronic renal failure after BMT.
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