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Related Experiment Videos

Mapping genes for psychiatric disorders and behavioral traits

L A McInnes1, V I Reus, N B Freimer

  • 1Neurogenetics Laboratory, San Francisco, California 94117, USA.

Current Opinion in Genetics & Development
|August 5, 1998
PubMed
Summary

Genetic studies in animals reveal complex behavior insights. However, human psychiatric genetics research, especially for common conditions, has lagged behind cognitive genetics advancements.

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Area of Science:

  • Behavioral genetics
  • Neurogenetics
  • Psychiatric genetics

Background:

  • Recent advances in non-human organism genetics offer insights into complex behaviors.
  • Progress in human cognitive genetics is notable.
  • Limited progress has been made in the genetic mapping of common psychiatric phenotypes.

Purpose of the Study:

  • To review the current state of genetic studies on complex behaviors.
  • To highlight the disparity in progress between human cognitive genetics and psychiatric genetics.

Main Methods:

  • Review of recent genetic studies in non-human organisms.
  • Analysis of developments in human behavioral and cognitive genetics.
  • Assessment of the current status of psychiatric genetics research.

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Main Results:

  • Significant insights into the genetic underpinnings of complex behaviors have emerged from studies in non-human models.
  • Human cognitive function genetics has seen encouraging advancements.
  • Genetic mapping for common psychiatric phenotypes remains a significant challenge.

Conclusions:

  • While animal models provide valuable data on behavior genetics, translating these findings to human psychiatric conditions requires further investigation.
  • Bridging the gap in human psychiatric genetics research is crucial for understanding and treating mental health disorders.