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[Thyroid tumors in obesity]

A Romiti1, R Buzzetti, A Salandri

  • 1Istituto di II Clinica Medica, Università degli Studi di Roma La Sapienza.

Minerva Endocrinologica
|August 6, 1998
PubMed
Summary
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Obese patients frequently have undiagnosed thyroid nodules, with a 31% prevalence. Of these, 8% were carcinomas, more common in females and adults with mild-to-moderate obesity.

Area of Science:

  • Endocrinology
  • Oncology
  • Obesity Medicine

Context:

  • Thyroid nodules are common, affecting 3-10% in the US and 4-10% in Europe.
  • Obesity is frequently associated with thyroid conditions.
  • Undiagnosed thyroid nodules are often incidentally discovered in obese patients.

Purpose:

  • To determine the prevalence of cold single nodules in obese patients.
  • To quantify the rate of previously undiagnosed nodules in this population.
  • To analyze the correlation between cold nodules and Body Mass Index (BMI), sex, and age.

Summary:

  • A study of 3248 obese patients over six years found a 31% prevalence of cold single thyroid nodules.
  • Notably, 83% of these nodules were previously undiagnosed.

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  • Carcinomas represented 8% of cold nodules, occurring more frequently in females (3:1 ratio) and in adults with mild-to-moderate obesity.

    • Impact:

    • Highlights a high, often undiagnosed, prevalence of thyroid nodules in obese individuals.
    • Suggests a need for increased thyroid screening in obese patient populations.
    • Provides data on risk factors (sex, age, obesity severity) for cold nodules and associated carcinomas.