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Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis
B S Menon1, I L Shuaib, M Zamari
1Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Annals of Tropical Paediatrics
|August 6, 1998
Abstract:
We describe a Malay girl with disseminated cryptococcosis affecting the lungs, liver, lymph nodes and bones. The diagnosis was made by culture of the bone marrow. Tests of immune function showed that she was HIV-negative but the CD4 percentage was persistently low. Idiopathic CD4+ T-lymphocytopenia was diagnosed. The child died despite two courses of anti-fungal therapy.