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Early pulmonary resection for localized Mycobacterium avium complex disease
Y Shiraishi1, K Fukushima, H Komatsu
1Department of Thoracic Surgery, National Tokyo Hospital, Kiyose, Japan.
The Annals of Thoracic Surgery
|August 6, 1998
Summary
Early pulmonary resection for localized Mycobacterium avium complex lung disease offers high success rates. This surgical approach can lead to sputum-negative status and low relapse rates, improving patient outcomes.
Area of Science:
- Pulmonary Medicine
- Infectious Diseases
- Surgical Oncology
Background:
- Antituberculous chemotherapy for Mycobacterium avium complex (MAC) lung disease has yielded disappointing results.
- Early-stage, localized MAC disease may benefit from surgical intervention.
- Pulmonary resection is a viable option for patients who can tolerate the procedure.
Purpose of the Study:
- To evaluate the efficacy and safety of pulmonary resection for localized Mycobacterium avium complex lung disease.
Main Methods:
- A retrospective analysis of 33 patients who underwent pulmonary resection for localized MAC disease between 1979 and 1996.
- Procedures included lobectomy (26), pleuropneumonectomy (1), segmentectomy (5), and wedge resection (1).
Main Results:
- No operative mortality was observed.
- 94% of patients achieved sputum-negative status post-surgery.
- Relapse rates were low (6%) among patients who became sputum-negative.
Conclusions:
- Pulmonary resection is a safe and effective treatment for localized Mycobacterium avium complex lung disease.
- Early consideration for surgical intervention is recommended for eligible patients.