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Metachronous colorectal cancers

O Fajobi1, C Y Yiu, S B Sen-Gupta

  • 1Department of Surgery, University College London Medical School, Whittington Hospital, UK.

The British Journal of Surgery
|August 6, 1998
PubMed
Summary
This summary is machine-generated.

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Metachronous colorectal cancers affect up to 9% of patients post-resection. Early detection via colonoscopy and surveillance are key for managing these secondary cancers.

Area of Science:

  • Oncology
  • Gastroenterology

Background:

  • Metachronous colorectal cancers develop in up to 9% of patients after initial resection.
  • Lack of consensus exists regarding the detection and management of these secondary cancers.

Purpose of the Study:

  • To review the literature on metachronous colorectal cancers.
  • To identify risk factors, detection methods, and management strategies.

Main Methods:

  • Exhaustive literature review of Medline and manual searches from 1966 to December 1997.
  • Inclusion of all relevant publications on metachronous colorectal cancers.

Main Results:

  • Identified risk factors include synchronous polyps/cancers, prior metachronous cancers, and hereditary non-polyposis colorectal cancer (HNPCC).

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  • Underlying causes for metachronous colorectal cancers require further elucidation.

    • Conclusions:

    • Preoperative and postoperative colonoscopy are crucial for identifying at-risk patients.
    • Total colectomy with ileorectal anastomosis is a consideration for select patients, especially those with HNPCC.