Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Assessment of bone density using ultrasonic backscatter

K A Wear1, B S Garra

  • 1Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20852, USA. KAW@CDRH.FDA.GOV

Ultrasound in Medicine & Biology
|August 8, 1998
PubMed
Summary

Ultrasonic backscatter shows promise for assessing bone status, offering a non-ionizing alternative to X-rays. This method correlates well with CT scans, suggesting its utility for evaluating bone architecture and density.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ultrasonic scattering from cancellous bone: a review.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2008
Same author

A method for improved standardization of in vivo calcaneal time-domain speed-of-sound measurements.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2008
Same author

The effects of frequency-dependent attenuation and dispersion on sound speed measurements: applications in human trabecular bone.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2008
Same author

The relationship between ultrasonic backscatter and bone mineral density in human calcaneus.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2008
Same author

Fundamental precision limitations for measurements of frequency dependence of backscatter: applications in tissue-mimicking phantoms and trabecular bone.

The Journal of the Acoustical Society of America·2002
Same author

Biomechanical response to acupuncture needling in humans.

Journal of applied physiology (Bethesda, Md. : 1985)·2001

Area of Science:

  • Biomedical Engineering
  • Medical Imaging
  • Materials Science

Background:

  • Current bone densitometry methods (X-ray, radioisotope) have limitations.
  • Ultrasound offers a low-cost, portable, non-ionizing alternative.
  • Ultrasonic backscatter may reveal microstructural information beyond attenuation and speed.

Purpose of the Study:

  • To investigate the effectiveness of ultrasonic backscatter for bone status assessment.
  • To explore ultrasonic backscatter as a complement or alternative to traditional densitometry.
  • To correlate ultrasonic backscatter data with computed tomography (CT) bone densitometry.

Main Methods:

  • Acquired ultrasonic backscatter data at 2.25 MHz.
  • Acquired CT bone densitometry data from 10 healthy volunteers.

Related Experiment Videos

  • Analyzed the correlation between CT and ultrasonic backscatter measurements.

    • Main Results:

    • A high correlation (r = 0.87, p < 0.001) was found between CT and ultrasonic backscatter.
    • The envelope signal-to-noise ratio suggests a large number of scatterers and specific statistical properties.
    • Results indicate ultrasonic backscatter is sensitive to microstructural variations.

    Conclusions:

    • Ultrasonic backscatter shows significant promise for bone status assessment.
    • It may serve as a valuable adjunct or substitute for existing ultrasonic and X-ray methods.
    • This technique could provide insights into bone architecture and fracture risk.