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Triplet pregnancy after intracytoplasmic sperm injection of cryopreserved oocytes: case report
E Young1, A Kenny, E Puigdomenech
1Instituto de Ginecología y Fertilidad (IFER), Buenos Aires, Argentina. IFER@COMNET.COM.AR
Objective:
To report a triplet pregnancy that occurred after intracytoplasmic injection of sperm into cryopreserved oocytes.
Design:
Case report.
Setting:
Instituto de Ginecología y Fertilidad (IFER), Buenos Aires, Argentina.
Patient:
A 36-year-old infertile patient with premature ovarian failure and a previous term pregnancy with fresh donated oocytes.
Intervention(S):
We administered leuprolide acetate for pituitary down-regulation followed by E2 valerianate in incremental doses until an endometrial lining of >8 mm was observed by ultrasound. Thawing of frozen donated oocytes, intracytoplasmic sperm injection (ICSI), and translaparoscopic fallopian tube ET also were performed. Natural micronized progesterone was administered intravaginally (600 mg/d) before ET.
Main Outcome Measure(S):
Ultrasound at the 8th week of gestation revealed a triplet pregnancy with active fetal heartbeats.
Result(S):
A triple intrauterine gestation was achieved with the use of microinjection into cryopreserved oocytes.
Conclusion(S):
This case illustrates the feasibility of oocyte cryopreservation for clinical use in the era of ICSI.