Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The isolated choroid plexus cyst

C L Morcos1, L D Platt, D E Carlson

  • 1Department of Obstetrics and Gynecology, Burns and Allen Research Institute of Cedars-Sinai Medical Center, University of California--Los Angeles School of Medicine, 90048, USA.

Obstetrics and Gynecology
|August 12, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of human chorionic gonadotropin and post-pregnancy persistent enhanced myometrial vascularity.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
Same author

Professional society recommended interventions for enhanced recovery after cesarean delivery in the United States: a multidisciplinary Delphi study.

International journal of obstetric anesthesia·2025
Same author

Correction of fetal umbilical vein flow imbalance following laser surgery for twin-twin transfusion syndrome.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2022
Same author

United States' experience in nuchal translucency measurement: variation according to provider characteristics in over five million ultrasound examinations.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2021
Same author

Accuracy of automated three-dimensional ultrasound imaging technique for fetal head biometry.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2020
Same author

Clinical experience of laboratory follow-up with noninvasive prenatal testing using cell-free DNA and positive microdeletion results in 349 cases.

Prenatal diagnosis·2018
Same journal

The Political Determinants of Obstetric Prescribing.

Obstetrics and gynecology·2026
Same journal

Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis.

Obstetrics and gynecology·2026
Same journal

Milestones in Motion: Vaginal Birth After Cesarean.

Obstetrics and gynecology·2026
Same journal

Ebola Virus in Pregnancy.

Obstetrics and gynecology·2026
Same journal

A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.

Obstetrics and gynecology·2026
Same journal

The Effects of Climate Change on Obstetric and Gynecologic Health.

Obstetrics and gynecology·2026
See all related articles

Isolated choroid plexus cysts in fetuses rarely indicate aneuploidy, but caution is advised. The risk of chromosomal abnormalities is similar whether the cyst is isolated or accompanied by other findings.

Area of Science:

  • Prenatal diagnostics
  • Fetal medicine
  • Genetics

Background:

  • Choroid plexus cysts are common findings during second-trimester ultrasound.
  • The association between choroid plexus cysts and fetal aneuploidy is a subject of ongoing research.
  • Distinguishing the significance of isolated cysts versus those with additional sonographic markers is crucial for accurate risk assessment.

Purpose of the Study:

  • To determine the karyotypic profiles of fetuses with choroid plexus cysts.
  • To compare the incidence of aneuploidy in fetuses with isolated choroid plexus cysts versus those with additional ultrasonographic findings.

Main Methods:

  • Retrospective review of 7617 second-trimester ultrasound examinations performed between 1993 and 1995.
  • Analysis of karyotypes and presence of other sonographic abnormalities in 210 fetuses identified with choroid plexus cysts.

Related Experiment Videos

  • Comparison of aneuploidy risk between isolated and non-isolated choroid plexus cyst groups.

    • Main Results:

    • 210 cases of choroid plexus cysts were identified (2.8% prevalence).
    • 86% of cases had isolated cysts; 14% had additional ultrasonographic findings.
    • Aneuploidy was rare, found in one fetus with an isolated cyst (trisomy 21) and one with additional findings (trisomy 18). The risk of aneuploidy was not significantly different between isolated and non-isolated cyst groups.

    Conclusions:

    • The incidence of aneuploidy in fetuses with isolated choroid plexus cysts is low.
    • The risk of aneuploidy associated with isolated choroid plexus cysts should be interpreted cautiously and considered alongside the baseline maternal risk.
    • Larger studies are needed to definitively ascertain any subtle differences in aneuploidy risk between isolated and non-isolated choroid plexus cysts.