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[Changes in the duodenal mucosa in Whipple's disease]
P N Sementsov1, S V Petrukhin, L I Butorova
1Pathomorphological Department, Central Pathology Laboratory of the Main Military Medical Division of the Defence Ministry, Moscow.
Arkhiv Patologii
|August 14, 1998
Abstract:
A case of Whipple's disease is described in a male patient of 43 who has been previously examined in different hospitals for six years. The diagnosis was established after surgery and histological examination of the duodenum biopsy. Infiltration of the tunica propria of the duodenum with PAS-positive macrophages was observed. Therapy with rondomycin in combination with GUMET-P produced a response but the recurrence took place after therapy. A new operation was followed by peritonitis and pneumonia which terminated in the patient's death.