Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A historical perspective on gestational diabetes

D R Hadden1

  • 1Sir George E. Clark Metabolic Unit, Royal Victoria Hospital, Belfast, Northern Ireland, U.K.

Diabetes Care
|August 15, 1998
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erroneous plasma "cortisol" values in Addison's disease : A problem of the fluorimetric assay of 11-OH corticosteroids.

Irish journal of medical science·2016
Same author

Hyperglycaemia in pregnancy: what's in a name?

Diabetic medicine : a journal of the British Diabetic Association·2013
Same author

Congenital anomalies in diabetic pregnancy: an important confirmation.

Diabetologia·2012
Same author

Prediabetes and the big baby.

Diabetic medicine : a journal of the British Diabetic Association·2008
Same author

Goat's rue - French lilac - Italian fitch - Spanish sainfoin: gallega officinalis and metformin: the Edinburgh connection.

The journal of the Royal College of Physicians of Edinburgh·2006
Same author

Recent advances in the monitoring and management of diabetic ketoacidosis.

QJM : monthly journal of the Association of Physicians·2005

Diabetes in pregnancy, first documented in 1823, led to the concept of gestational diabetes. Maternal hyperglycemia poses risks to the baby, driving global research into this maternal-fetal interaction.

Area of Science:

  • Obstetrics and Gynecology
  • Endocrinology
  • Perinatal Medicine

Background:

  • The historical understanding of diabetes in pregnancy dates back to 1823, with early observations linking maternal diabetic conditions to pregnancy outcomes.
  • The misconception that diabetes was solely a symptom of pregnancy contributed to the development of the concept of gestational diabetes.
  • Early research in Boston and Los Angeles identified risks associated with carbohydrate intolerance during pregnancy.

Observation:

  • Extreme fetal macrosomia was noted in the earliest recorded instances of diabetes in pregnancy.
  • Maternal hyperglycemia, even in lesser degrees, was recognized as a significant risk factor for adverse fetal outcomes.
  • Studies highlighted the complex interaction between maternal metabolic status and fetal development.

Findings:

Related Experiment Videos

  • The historical progression of understanding diabetes in pregnancy has evolved from symptom association to recognizing it as a distinct condition.
  • Recognition of maternal hyperglycemia as a risk factor has spurred significant research into its effects on fetal growth and well-being.
  • Early epidemiological studies laid the groundwork for current global interest in managing hyperglycemia during pregnancy.

Implications:

  • Understanding the historical context of diabetes in pregnancy is crucial for refining current diagnostic and management strategies.
  • Continued research into maternal-fetal interactions in hyperglycemia is essential for improving perinatal outcomes.
  • The evolution of the concept of gestational diabetes underscores the importance of ongoing scientific inquiry in obstetrics and endocrinology.