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[Imaging aspects of primary cerebral lymphoma]
P Vandermarcq1, C Drapeau, J C Ferrie
1Servive de Radiologie A, CHU, Poitiers.
Neuro-Chirurgie
|January 1, 1997
Summary
This study analyzed CT and MRI scans of 196 lymphomatous lesions in 127 patients. Key imaging features like location and enhancement patterns strongly suggest lymphoma, aiding diagnosis.
Area of Science:
- Neuroradiology
- Oncologic Imaging
- Diagnostic Radiology
Context:
- Lymphoma is a significant cause of brain lesions.
- Accurate and timely diagnosis is crucial for patient management.
- Distinguishing lymphomatous lesions from other brain pathologies can be challenging.
Purpose:
- To review the CT and MRI characteristics of histologically proven lymphomatous lesions.
- To identify imaging features suggestive of primary central nervous system lymphoma (PCNSL).
- To correlate imaging findings with lesion location, size, and enhancement patterns.
Summary:
- The study reviewed 196 lymphomatous lesions in 127 patients using CT and MRI.
- Most lesions were single, supratentorial, >1 cm, with regular demarcation and mild edema.
- Infiltrative patterns, basal ganglion/corpus callosum involvement, and ependymal/mirror patterns were highly suggestive of lymphoma.
- CT post-contrast enhancement was nearly universal (99%) and often homogeneous (82%).
Impact:
- Provides valuable insights into the typical imaging appearance of CNS lymphoma.
- Aids radiologists in differentiating lymphomatous lesions from other intracranial masses.
- Contributes to improved diagnostic accuracy and potentially earlier treatment initiation for lymphoma patients.