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The chemical synthesis of E. coli tRNA(Lys) anticodon loop fragment and its analogues
1Institute of Organic Chemistry, Technical University of Lódź, Poland. ejsochac@ck-sg.p.lodz.pl
Abstract:
E. coli tRNA(Lys) anticodon loop fragment (Umnm5s2UUUt6A) 1 and its analogues 2-6 were synthesized by the classical phosphotriester approach in solution. The preparation of suitably protected derivatives of N6-threonylcarbamoyladenosine 18 is also described.