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Sequence selective interaction between nucleotides and intercalators bound to water soluble dextran: an application
1Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan. shirai@imcbns.iam.u-tokyo.ac.jp
Nucleosides & Nucleotides
|August 26, 1998
Abstract:
The analysis of association constant between dextran coupled intercalators and nucleotides revealed the base- and sequence-selective affinity to mono- and dinucleotides in aqueous solution. Acridine bound CH-Sepharose 4B, designed as the affinity stationary phase for nucleotides, also showed base- and sequence-selective affinity.