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Thalamotomy for parkinsonian tremor
B P Brophy1, T J Kimber, P D Thompson
1Department of Neurology, Royal Adelaide Hospital, Australia. pauline.archer@flinders.edu.au
Stereotactic and Functional Neurosurgery
|January 1, 1997
Summary
Thalamotomy effectively treated parkinsonian tremor in most patients, with 66% achieving good outcomes. Electrode stimulation confirmed accurate targeting, though some experienced new deficits.
Area of Science:
- Neurosurgery
- Neurology
- Movement Disorders
Background:
- Parkinsonian tremor significantly impacts quality of life.
- Thalamotomy is a potential treatment for refractory tremor.
Purpose of the Study:
- To evaluate the efficacy and safety of thalamotomy for parkinsonian tremor.
- To assess the utility of intraoperative stimulation for target verification.
Main Methods:
- Twenty-five patients with parkinsonian tremor underwent thalamotomy.
- Lesioning electrode stimulation was used to confirm target localization.
- Outcomes and adverse events were systematically recorded.
Main Results:
- A good outcome was achieved in 66% of the patients treated.
- Three patients (12%) experienced significant new neurological deficits post-procedure.
- Intraoperative stimulation through the lesioning electrode proved effective for target localization.
Conclusions:
- Thalamotomy is a viable option for managing parkinsonian tremor, offering good results in a majority of cases.
- Careful target localization using electrode stimulation is crucial to minimize risks.
- Potential for new deficits necessitates careful patient selection and surgical planning.