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Chemosensory function and dysfunction

A I Spielman1

  • 1Basic Science Division, New York University College of Dentistry, New York 10010, USA.

Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists
|August 26, 1998
PubMed
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Chemosensory disorders, affecting taste and smell, impact millions and are often linked to aging or specific conditions. While diagnosis has improved, effective treatments remain limited, highlighting the need for further research.

Area of Science:

  • Neuroscience
  • Sensory Biology
  • Otorhinolaryngology

Background:

  • Taste and smell are vital for nutrition, food enjoyment, metabolism, and quality of life.
  • Significant advancements have been made in understanding the basic mechanisms of gustatory and olfactory systems.
  • Chemosensory disorders affect at least 2 million Americans, a number expected to rise with an aging population.

Purpose of the Study:

  • To clarify the molecular events underlying taste and smell disorders by understanding normal chemosensory function.
  • To review the current state of diagnosis and treatment for chemosensory disorders.
  • To identify areas for future research in chemosensory science.

Main Methods:

  • Review of current scientific literature on gustatory and olfactory systems.

Related Experiment Videos

  • Analysis of the prevalence and causes of chemosensory disorders.
  • Evaluation of diagnostic and therapeutic approaches.
  • Main Results:

    • Smell disorders are more common than taste disturbances, often due to aging, infections, sinus diseases, or nerve damage.
    • Identifiable causes exist for most chemosensory complaints.
    • Diagnosis has improved, but treatments are primarily effective for reversible conditions.

    Conclusions:

    • Further research is crucial for a deeper understanding of chemosensory mechanisms.
    • Improved diagnostic procedures and broader dissemination of knowledge are needed.
    • Developing more effective treatments for chemosensory disorders is a priority.