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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
Published on: June 2, 2015
Deep venous thrombosis: gradient-recalled-echo MR imaging changes over time--experience in 10 patients
C E Spritzer1, P Trotter, H D Sostman
1Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
Radiology
|September 2, 1998
Summary
Gradient-recalled-echo (GRE) magnetic resonance (MR) imaging reveals changes in deep venous thrombosis over time. These findings help differentiate acute deep venous thrombosis from residual changes of prior events.
Area of Science:
- Radiology and Imaging
- Vascular Medicine
- Medical Diagnostics
Background:
- Deep venous thrombosis (DVT) diagnosis and monitoring are crucial for patient outcomes.
- Distinguishing acute DVT from chronic changes can be challenging with conventional imaging.
- Gradient-recalled-echo (GRE) magnetic resonance (MR) imaging offers unique capabilities for visualizing thrombus characteristics.
Purpose of the Study:
- To characterize the temporal changes of intraluminal thrombus in lower extremities using GRE MR imaging.
- To establish imaging criteria with GRE MR to differentiate acute DVT from previous DVT.
Main Methods:
- GRE MR imaging was performed on 10 patients (4 women, 6 men; age 38-76) 2-4 weeks after DVT diagnosis.
- Ultrasonography was used for confirmation in 8 patients.
- Follow-up ranged from 3 months to 1.5 years, with evaluation of thrombus evidence, signal intensity, and appearance.
Main Results:
- Acute thrombosis presented as vessel occlusion or filling defect with normal or larger luminal diameter.
- Acute thrombus signal intensity showed an initial decrease followed by an increase over time.
- Residual changes included web formation, luminal narrowing, wall thickening, and slow flow; 3 vessels returned to normal.
Conclusions:
- GRE MR imaging effectively demonstrates the evolution of venous thrombus over time.
- Established GRE MR imaging criteria can aid in distinguishing acute DVT from the sequelae of previous DVT.
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