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Recurrent vaginal candidiasis and allergic rhinitis: a common association
1Paula Moraes, Felipe dos Santos, Belo Horizonte, MG, Brazil.
Summary
Recurrent vaginal candidiasis is strongly linked to perennial allergic rhinitis in women. Many patients with this condition also show atopic tendencies and positive allergy skin tests.
Area of Science:
- Allergy and Immunology
- Dermatology
- Gynecology
Background:
- Recurrent vaginal candidiasis (RVC) is often associated with hypersensitivity.
- Gynecologists observe high rates of allergic rhinitis and family allergies in RVC patients.
- This study investigates the link between RVC and allergic conditions.
Purpose of the Study:
- To determine the association between RVC and perennial allergic rhinitis.
- To explore the allergic profiles of women diagnosed with RVC.
- To understand the allergic characteristics of RVC.
Main Methods:
- Prospective study of 95 RVC patients and 100 controls over 28 months.
- Standard allergy medical history and physical examination for all participants.
- Immediate skin tests with inhalant allergens and Candida albicans were performed.
Main Results:
- 71% of RVC patients had allergic rhinitis, compared to 42% in controls (P < .0001).
- No association was found between RVC and asthma.
- RVC patients showed high rates of positive skin tests to inhalant allergens (50%) and Candida albicans (55%), with 73% having a family history of allergies.
Conclusions:
- A statistically significant association exists between RVC and perennial allergic rhinitis.
- Women with RVC frequently exhibit atopic characteristics.
- Findings suggest an allergic basis for some cases of RVC.