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Blastomycosis in northeast Tennessee

J E Vasquez¹, J B Mehta, R Agrawal

¹James H. Quillen Veterans Affairs Medical Center, Department of Internal Medicine, East Tennessee State University College of Medicine, Johnson City 37614, USA.

|September 3, 1998

Summary

Blastomycosis cases in northeast Tennessee quadrupled between 1980-1995, linked to construction. Clinicians must recognize this increasing endemic fungal infection.

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Area of Science:

Medical Mycology
Infectious Diseases
Public Health Epidemiology

Background:

Blastomycosis is a serious fungal infection caused by *Blastomyces dermatitidis*.
Geographic distribution and incidence rates can fluctuate, influenced by environmental and demographic factors.

Purpose of the Study:

To investigate the epidemiologic and clinical characteristics of blastomycosis in northeast Tennessee.
To identify trends in incidence and potential contributing factors.

Main Methods:

Retrospective review of 72 confirmed blastomycosis cases from 1980 to 1995 in northeast Tennessee.
Analysis of patient demographics, clinical presentation, treatment, and incidence rates over time.

Main Results:

Incidence of blastomycosis quadrupled from 1980-1995, with a significant increase noted between 1988-1995.
Pulmonary involvement was most common (61 cases), with multiorgan involvement in 17 cases.
A sharp increase in cases correlated with new construction projects in three specific counties.

Conclusions:

Blastomycosis is endemic and increasing in northeast Tennessee, with a temporal association to construction.
Healthcare providers in the region need heightened awareness for diagnosing and managing blastomycosis.

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