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Microcirculation architecture of metastases from primary ciliary body and choroidal melanomas
V Rummelt1, M G Mehaffey, R J Campbell
1Department of Ophthalmology, University of Erlangen-Nürnberg.
American Journal of Ophthalmology
|September 4, 1998
Abstract
Purpose:
To describe the microcirculation architecture of metastatic choroidal and ciliary body melanoma.
Method:
Histologic sections of 35 metastases from 19 primary melanomas were stained to demonstrate microcirculation.
Result:
The appearance of microcirculatory networks in metastases is independent of the target organ but associated with the size of the metastatic deposit (estimated coefficient = 0.5959; SE = 0.3024; P = .0488).
Conclusion:
The microcirculatory patterns of primary uveal melanomas that are associated with metastatic behavior appear in foci of metastasis, regardless of the site of dissemination.