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Structure of the P-type ATPases
W Kühlbrandt1, M Auer, G A Scarborough
1Max-Planck-Institut für Biophysik, Abteilung Strukturbiologie, Frankfurt am Main, Germany. kuehlbrandt@biophys.mpg.de
Current Opinion in Structural Biology
|September 8, 1998
Abstract:
Electron cryocrystallography of precipitant-induced two-dimensional surface crystals of the neurospora plasma membrane H+ - ATPase and tubular crystals of the sarcoplasmic reticulum Ca(2+)-ATPase has recently yielded structure maps for these ion transporters at a resolution of about 8 A. The membrane-embedded regions of these closely related enzymes are similar, but the cytoplasmic regions appear to be significantly different.