Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The "gauntlet" of pellagra

S Isaac1

  • 1Saint Barnabas Medical Center, Livingston, New Jersey 07039, USA.

International Journal of Dermatology
|September 10, 1998
PubMed
Summary

This case study highlights pellagra, a niacin deficiency disease, in an alcoholic Filipino man. Prompt treatment with nicotinamide effectively resolved the characteristic skin eruption and diarrhea.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Update on gene fusions and the emerging clinicopathological landscape of peritoneal and pleural mesotheliomas and other neoplasms.

ESMO open·2024
Same author

Intestinal Conventional Ultrasonography, Contrast-Enhanced Ultrasonography and Magnetic Resonance Enterography in Assessment of Crohn's Disease Activity: A Comparison with Surgical Histopathology Analysis.

Digestive diseases and sciences·2021
Same author

Immunohistochemical evaluation of two antibodies against PD-L1 and prognostic significance of PD-L1 expression in epithelioid peritoneal malignant mesothelioma: A RENAPE study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2017
Same author

The RENAPE observational registry: rationale and framework of the rare peritoneal tumors French patient registry.

Orphanet journal of rare diseases·2017
Same author

Diffuse malignant peritoneal mesothelioma: Evaluation of systemic chemotherapy with comprehensive treatment through the RENAPE Database: Multi-Institutional Retrospective Study.

European journal of cancer (Oxford, England : 1990)·2016
Same author

Intraperitoneal-Free Cancer Cells Represent a Major Prognostic Factor in Colorectal Peritoneal Carcinomatosis.

Diseases of the colon and rectum·2016

Area of Science:

  • Dermatology
  • Nutritional Science

Background:

  • Pellagra is a disease resulting from niacin (vitamin B3) deficiency.
  • Alcoholism is a known risk factor for nutritional deficiencies, including pellagra.

Observation:

  • A 48-year-old Filipino man with a 2-year history of skin eruption and diarrhea presented with symmetrical, erythematous rash on sun-exposed areas.
  • The rash distribution included hands, forearms, neck (casal's necklace), legs, and feet.
  • The patient had a history of alcoholism but no cognitive impairment.

Findings:

  • Clinical diagnosis of pellagra was established based on the characteristic dermatological presentation and symptoms.
  • Treatment with nicotinamide (500 mg daily) led to rapid improvement and complete resolution of the eruption within two weeks.

Implications:

  • This case underscores the importance of recognizing pellagra in patients with risk factors like alcoholism, even with atypical presentations.
  • Early diagnosis and treatment with nicotinamide are crucial for effective management and prevention of complications.
  • Highlights the diagnostic value of characteristic skin findings in nutritional deficiency diseases.

Related Experiment Videos