[Tissue polypeptide antigen and carcinoembryonic antigen in bladder neoplasms]
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Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
B Krajewska1, W Stelmach, W Lutz
1Zakładu Diagnostyki Laboratoryjnej, Instytutu Medycyny Pracy, Lodzi.
Abstract:
The study was designed to evaluate the effect of acetilation phenotype and smoking on the concentration of tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA) in serum of patients with neoplasm of bladder. The study covered a group of 76 patients suffering from neoplasm of bladder and a control group composed of 46 persons. Acetylation phenotype as well as TPA and CEA concentrations in serum were determined. In addition, data on smoking habit were collected. The study indicated significant difference in TPA values in both group while there was no difference in regard to CEA values. It was found that in patients with neoplasm of bladder both acetylation phenotype and smoking affect significantly TPA concentration in serum.
